CHX-Plus™ by Vista-Dental
2% Chlorhexidine Gluconate Solution
 
Description
Enhanced 2% Chlorhexidine Gluconate Solution (Patented)
Kills multispecies biofilm 2X faster than standard 2% chlorhexidine
It contains 2% Chlorhexidine Gluconate plus powerful wetting agents and proprietary surface modifiers to improve the depth of penetration and kills bacteria 10X faster than normal 2% Chlorhexidine.
Evaluation of the effect of two chlorhexidine preparations on biofilm bacteria in vitro: a three-dimensional quantitative analysis.
This study developed a biofilm model that closely mimicked in vivo biofilm to determine its susceptibility to endodontic antimicrobial irrigants by three-dimensional quantitative analysis. Collagen-coated hydroxyapatite (C-HA) and uncoated hydroxyapatite (HA) disks were inoculated with a dispersed subgingival plaque for three weeks. Thick biofilms rich in spirochetes were formed on both substrates. Biofilms were subjected to 1-, 3-, and 10-minute exposures to CHX-Plus™ (Vista Dental Products, Racine, WI) and 2% chlorhexidine (CHX). After treatment, the volume ratio of dead bacteria to all bacteria in biofilms, indicated by the ratio of red and (red + green) fluorescence, was analyzed by confocal laser scanning microscopy for each medicament.
The proportion of killed bacteria depended on the type of irrigant and time of exposure in both C-HA and HA biofilm models (p = 0.00). CHX-Plus™ showed higher levels of bactericidal activity at all exposure times than 2% CHX (p < 0.001). The C-HA biofilm was thicker than the HA biofilm. Less bacteria were killed in C-HA biofilm than in the HA model.
J Endod. 2009 Jan;35(7):981-5. Epub 2008 Nov 7. Shen Y, Qian W, Chung C, Olsen I, Haapasalo M. Division of Endodontics, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, Canada.
 
Packing
1.2 ml Syringe
Made in the USA